Multiple Sclerosis Treatment Options: Why Exercise Should Be Part of Every MS Plan
- Sven Rees
- Jun 8
- 3 min read

Navigating MS with a Holistic Approach
If you or someone you love has been diagnosed with Multiple Sclerosis (MS), the treatment options can feel overwhelming. Medications, scans, appointments—and still, symptoms like fatigue, weakness, or imbalance can linger.
At Exercise Matters, we believe the best outcomes come from a combined approach. Medications can slow the disease, but exercise is what helps you stay strong, mobile, and independent. In this guide, we break down the most common MS treatment options and explain why exercise is essential.
Core Treatment Options for MS
MS treatment is typically split into three categories:
1. Disease-Modifying Therapies (DMTs)
These medications aim to reduce relapse rates and delay disability progression.
Interferon beta (e.g., Avonex, Rebif)
Glatiramer acetate (Copaxone)
Oral therapies (e.g., Tecfidera, Gilenya)
Infusions (e.g., Ocrevus, Tysabri)
Evidence: DMTs reduce relapses by 30–70% depending on the medication type (Goodin et al., 2021).
2. Symptom Management Medications
To manage specific challenges:
Muscle relaxants for spasticity (e.g., Baclofen)
Antidepressants for mood and fatigue
Medications for bladder, bowel, or cognitive symptoms
3. Rehabilitation Therapies
This is where Exercise Physiology comes in.
Physiotherapy for mobility and stretching
Occupational therapy for daily tasks
Exercise Physiology for strength, fatigue, endurance, and balance
Speech therapy (if communication is affected)
Why Exercise Is Part of MS Treatment
1. Exercise Supports Brain Health
Aerobic and resistance training enhance neuroplasticity—the brain's ability to form new connections.
Research: Motl et al. (2019) found that consistent aerobic exercise reduced disease progression markers and improved brain volume retention.
2. Builds Strength and Endurance
Targeted strength training counteracts muscle loss and mobility decline.
3. Reduces Fatigue
Contrary to common fears, moderate exercise reduces MS fatigue. It improves energy efficiency and oxygen transport.
4. Improves Balance and Gait
Exercise targeting postural control reduces fall risk and improves walking stability.
5. Boosts Mood, Memory, and Mental Resilience
Exercise releases brain-derived neurotrophic factor (BDNF), which supports memory, attention, and mental health.
The Exercise Matters Approach to MS Care
We collaborate with your neurologist and allied health team to create a program that aligns with your symptoms, goals, and treatment phase.
Our Programs May Include:
Seated or supported resistance training
Interval-based aerobic activity (bike, rowing, treadmill)
Dual-task coordination drills
Balance retraining and posture support
Fatigue pacing and temperature regulation strategies
Importantly: We adapt sessions to your energy levels, relapse history, and medication cycles.
Case Study: Mel, 35, Relapsing-Remitting MS
Mel was on DMTs but still experienced frequent fatigue and mild leg weakness. We introduced 2x/week Exercise Physiology focused on:
Energy conservation pacing
Core and gluteal strength
Supported cardio (seated bike)
After 12 weeks:
Her fatigue dropped by 40% (from 8/10 to 5/10)
She reported walking further before needing rest
Her neurologist observed improved gait control at her next review
Frequently Asked Questions
1. Can I start exercise if I’m already on medication?
Yes. In fact, exercise can enhance the effectiveness of medication by improving the way your body manages symptoms.
2. What’s the difference between Exercise Physiology and Physiotherapy?
EP focuses on long-term strength, endurance, and self-managed exercise. Physio often focuses on injury, joint mobility, and acute rehabilitation.
3. Is exercise safe during a flare-up?
We adjust programs to suit your recovery. Light activity and stretching can support circulation and mood during milder flares.
4. Will I need to exercise forever?
Exercise is a long-term investment. Just like brushing your teeth, it becomes part of a healthy routine to maintain what you’ve gained.
5. Is this covered by NDIS or Medicare?
Yes. We work with NDIS, Medicare chronic disease plans, and private health funds.
Start Your Integrated MS Plan
Living with MS requires a team—and a plan. Let us help you move with more strength, more confidence, and less fatigue.
📞 Call (07) 5448 3532 🌐 www.exercisematters.healthcare
References:
Goodin DS et al. (2021). The effectiveness of disease-modifying therapies in MS. Neurology.
Motl RW, Sandroff BM. (2019). Exercise and MS progression. Lancet Neurology.
Latimer-Cheung AE et al. (2013). Physical activity guidelines for MS. Archives of Physical Medicine.
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